That has changed.
It sounds like you're referring to a recent or interesting post about a of Lossless Scaling being updated. lossless scaling portable updated
The portable edition uses:
If you’re a gamer on the move, you know the struggle: trying to run the latest titles on a handheld or a modest laptop often means sacrificing visual clarity for performance. That’s where Lossless Scaling The Ultimate Guide to Lossless Scaling Portable: Updated
C:\Program Files (x86)\Steam\steamapps\common\Lossless Scaling) to another location, and it will run portably. This is the safest and recommended method.